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Promethazine and daridorexant both equally boost sedation. Modify Therapy/Check Intently. Coadministration will increase hazard of CNS depression, which can cause additive impairment of psychomotor efficiency and lead to daytime impairment. Respiratory melancholy bringing about arrest, coma, and Loss of life has occurred with using codeine antitussives in young small children, https://wockusa.com/product/wockhardt-promethazine-with-codeine-oral-solution/

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