Proanthocyanidins are thought to be responsible for the antibacterial impact of cranberry, Which explains why their focus in the cranberry extract is important. The authors of this paper cite experimental proof, moreover a survey of 400 Expecting Girls which didn't obtain any adverse effects associated with cranberry juice usage. https://bookmarkcolumn.com/story20019147/%D8%A8%D9%88%D8%AB%D8%A7%D8%AA-%D8%A7%D9%84%D9%85%D8%B9%D8%A7%D8%B1%D8%B6-secrets