Critically ill individuals: Nitrous oxide inactivates methionine synthase by using oxidation of the cobalt in vitamin B12 and could bring about megaloblastic anemia. This enzyme is important for vitamin B12 and folate metabolism and performs a role in DNA and RNA synthesis along with the synthesis of other substances. 2O.[43] https://zandertfcne.blogpixi.com/37500851/the-5-second-trick-for-nitrous-oxide-canisters